Macromolecular X-ray Crystallography

Preclinical Drug Development Unit is a professional partner responsible for Macromolecular X-ray Crystallography.

Crystallization and crystal optimization

We offer services:

  • Crystallization and crystal optimization – the facility is equipped with the Phoenix and Oryx robots for high throughput automated screening of crystal growth in 96-well format and volumes as small as 100 nL.
  • Crystallization of proteins, protein – inhibitor complexes, protein – nucleic acids complexes.
  • X-ray diffraction data collection at sychrotron beamlines.
  • Solution and refinement of protein and protein-ligand structures to the quality required for PDB deposition.